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Cryo-EM structure of eastern equine encephalitis virus in complex with heparan sulfate analogues

Eastern equine encephalitis virus (EEEV), a mosquito-borne icosahedral alphavirus found mainly in North America, causes human and equine neurotropic infections. EEEV neurovirulence is influenced by the interaction of the viral envelope protein E2 with heparan sulfate (HS) proteoglycans from the host...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Chen, Chun-Liang, Hasan, S. Saif, Klose, Thomas, Sun, Yingyuan, Buda, Geeta, Sun, Chengqun, Klimstra, William B., Rossmann, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183182/
https://ncbi.nlm.nih.gov/pubmed/32245806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1910670117
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