Demarcation of Topologically Associating Domains Is Uncoupled from Enriched CTCF Binding in Developing Zebrafish

CCCTC-binding factor (CTCF) is a conserved architectural protein that plays crucial roles in gene regulation and three-dimensional (3D) chromatin organization. To better understand mechanisms and evolution of vertebrate genome organization, we analyzed genome occupancy of CTCF in zebrafish utilizing...

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Veröffentlicht in:iScience
Hauptverfasser: Pérez-Rico, Yuvia A., Barillot, Emmanuel, Shkumatava, Alena
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7182764/
https://ncbi.nlm.nih.gov/pubmed/32334414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101046
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