SLC6A14, a Na(+)/Cl(−)-coupled amino acid transporter, functions as a tumor promoter in colon and is a target for Wnt signaling

SLC6A14 is a Na(+)/Cl(−)-coupled transporter for neutral and cationic amino acids. It is expressed at basal levels in the normal colon but is up-regulated in colon cancer. However, the relevance of this up-regulation to cancer progression and the mechanisms involved in the up-regulation remain unkno...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Sikder, Mohd O. F., Sivaprakasam, Sathish, Brown, Timothy P., Thangaraju, Muthusamy, Bhutia, Yangzom D., Ganapathy, Vadivel
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2020
Assuntos:
Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7182441/
https://ncbi.nlm.nih.gov/pubmed/32219372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20200099
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