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Consequences of NaCT/SLC13A5/mINDY deficiency: good versus evil, separated only by the blood–brain barrier

NaCT/SLC13A5 is a Na(+)-coupled transporter for citrate in hepatocytes, neurons, and testes. It is also called mINDY (mammalian ortholog of ‘I'm Not Dead Yet’ in Drosophila). Deletion of Slc13a5 in mice leads to an advantageous phenotype, protecting against diet-induced obesity, and diabetes. I...

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Dades bibliogràfiques
Publicat a:Biochem J
Autors principals: Kopel, Jonathan J., Bhutia, Yangzom D., Sivaprakasam, Sathish, Ganapathy, Vadivel
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7868109/
https://ncbi.nlm.nih.gov/pubmed/33544126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20200877
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