Slc5a8, a Na(+)-coupled high-affinity transporter for short-chain fatty acids, is a conditional tumor suppressor in colon that protects against colitis and colon cancer under low-fiber dietary conditions

Mammalian colon harbors trillions of bacteria under physiologic conditions; this symbiosis is made possible because of a tolerized response from the mucosal immune system. The mechanisms underlying this tolerogenic phenomenon remain poorly understood. Here we show that Slc5a8, a Na(+)-coupled high-a...

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Publicado en:Biochem J
Autores principales: Gurav, Ashish, Sivaprakasam, Sathish, Bhutia, Yangzom D., Boettger, Thomas, Singh, Nagendra, Ganapathy, Vadivel
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943859/
https://ncbi.nlm.nih.gov/pubmed/25984582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20150242
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