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DOT: Gene-set analysis by combining decorrelated association statistics

Historically, the majority of statistical association methods have been designed assuming availability of SNP-level information. However, modern genetic and sequencing data present new challenges to access and sharing of genotype-phenotype datasets, including cost of management, difficulties in cons...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Vsevolozhskaya, Olga A., Shi, Min, Hu, Fengjiao, Zaykin, Dmitri V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7182280/
https://ncbi.nlm.nih.gov/pubmed/32287273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007819
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