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Assessing the Probability that a Finding Is Genuine for Large-Scale Genetic Association Studies

Genetic association studies routinely involve massive numbers of statistical tests accompanied by P-values. Whole genome sequencing technologies increased the potential number of tested variants to tens of millions. The more tests are performed, the smaller P-value is required to be deemed significa...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Kuo, Chia-Ling, Vsevolozhskaya, Olga A., Zaykin, Dmitri V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425705/
https://ncbi.nlm.nih.gov/pubmed/25955023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124107
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