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Assessing the Probability that a Finding Is Genuine for Large-Scale Genetic Association Studies

Genetic association studies routinely involve massive numbers of statistical tests accompanied by P-values. Whole genome sequencing technologies increased the potential number of tested variants to tens of millions. The more tests are performed, the smaller P-value is required to be deemed significa...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kuo, Chia-Ling, Vsevolozhskaya, Olga A., Zaykin, Dmitri V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425705/
https://ncbi.nlm.nih.gov/pubmed/25955023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124107
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