Smooth muscle cell reprogramming in aortic aneurysms

The etiology of aortic aneurysms is poorly understood, but it is associated with atherosclerosis, hypercholesterolemia, and abnormal TGFβ signaling in smooth muscle. Here we investigated the interactions between these different factors in aortic aneurysm development and identified a key role for smo...

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Udgivet i:Cell Stem Cell
Main Authors: Chen, Pei-Yu, Qin, Lingfeng, Li, Guangxin, Malagon-Lopez, Jose, Wang, Zheng, Bergaya, Sonia, Gujja, Sharvari, Caulk, Alexander W., Murtada, Sae-Il, Zhang, Xinbo, Zhuang, Zhen W., Rao, Deepak A., Wang, Guilin, Tobiasova, Zuzana, Jiang, Bo, Montgomery, Ruth R, Sun, Lele, Sun, Hongye, Fisher, Edward A., Gulcher, Jeffrey R., Fernandez-Hernando, Carlos, Humphrey, Jay D., Tellides, George, Chittenden, Thomas W., Simons, Michael
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7182079/
https://ncbi.nlm.nih.gov/pubmed/32243809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.02.013
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