Smooth muscle cell reprogramming in aortic aneurysms

The etiology of aortic aneurysms is poorly understood, but it is associated with atherosclerosis, hypercholesterolemia, and abnormal TGFβ signaling in smooth muscle. Here we investigated the interactions between these different factors in aortic aneurysm development and identified a key role for smo...

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Publicado no:Cell Stem Cell
Main Authors: Chen, Pei-Yu, Qin, Lingfeng, Li, Guangxin, Malagon-Lopez, Jose, Wang, Zheng, Bergaya, Sonia, Gujja, Sharvari, Caulk, Alexander W., Murtada, Sae-Il, Zhang, Xinbo, Zhuang, Zhen W., Rao, Deepak A., Wang, Guilin, Tobiasova, Zuzana, Jiang, Bo, Montgomery, Ruth R, Sun, Lele, Sun, Hongye, Fisher, Edward A., Gulcher, Jeffrey R., Fernandez-Hernando, Carlos, Humphrey, Jay D., Tellides, George, Chittenden, Thomas W., Simons, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7182079/
https://ncbi.nlm.nih.gov/pubmed/32243809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.02.013
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