Targeting Calcium Release-Activated Calcium (CRAC) Channel is not sufficient to prevent rejection in Non-Human Primate Kidney Transplantation

[BACKGROUND]: Calcineurin inhibitors successfully control rejection of transplanted organs, but also cause nephrotoxicity. This study, using a rhesus monkey renal transplantation model, sought to determine the applicability of a new immunomodulatory drug inhibiting the store-operated calcium release...

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Gepubliceerd in:Transplantation
Hoofdauteurs: Kwun, Jean, Ezekian, Brian, Manook, Miriam, Park, Jaeberm, Yoon, Janghoon, Freischlag, Kyle, Song, Mingqing, Farris, Alton B, Sloan-Lancaster, Joanne, Fortier, Caroline, Rao, Patricia E., Knechtle, Stuart J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7182068/
https://ncbi.nlm.nih.gov/pubmed/32317615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000003078
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