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Genome-Scale Metabolic Modeling of Glioblastoma Reveals Promising Targets for Drug Development

Glioblastoma (GBM) is an aggressive type of brain cancer with a poor prognosis for affected patients. The current line of treatment only gives the patients a survival time of on average 15 months. In this work, we use genome-scale metabolic models (GEMs) together with other systems biology tools to...

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發表在:Front Genet
Main Authors: Larsson, Ida, Uhlén, Mathias, Zhang, Cheng, Mardinoglu, Adil
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181968/
https://ncbi.nlm.nih.gov/pubmed/32362913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00381
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