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Identification of anticancer drugs for hepatocellular carcinoma through personalized genome‐scale metabolic modeling

Genome‐scale metabolic models (GEMs) have proven useful as scaffolds for the integration of omics data for understanding the genotype–phenotype relationship in a mechanistic manner. Here, we evaluated the presence/absence of proteins encoded by 15,841 genes in 27 hepatocellular carcinoma (HCC) patie...

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Detalhes bibliográficos
Main Authors: Agren, Rasmus, Mardinoglu, Adil, Asplund, Anna, Kampf, Caroline, Uhlen, Mathias, Nielsen, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017677/
https://ncbi.nlm.nih.gov/pubmed/24646661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/msb.145122
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