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Identifying anti-growth factors for human cancer cell lines through genome-scale metabolic modeling

Human cancer cell lines are used as important model systems to study molecular mechanisms associated with tumor growth, hereunder how genomic and biological heterogeneity found in primary tumors affect cellular phenotypes. We reconstructed Genome scale metabolic models (GEMs) for eleven cell lines b...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Ghaffari, Pouyan, Mardinoglu, Adil, Asplund, Anna, Shoaie, Saeed, Kampf, Caroline, Uhlen, Mathias, Nielsen, Jens
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313100/
https://ncbi.nlm.nih.gov/pubmed/25640694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08183
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