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Identifying anti-growth factors for human cancer cell lines through genome-scale metabolic modeling

Human cancer cell lines are used as important model systems to study molecular mechanisms associated with tumor growth, hereunder how genomic and biological heterogeneity found in primary tumors affect cellular phenotypes. We reconstructed Genome scale metabolic models (GEMs) for eleven cell lines b...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Ghaffari, Pouyan, Mardinoglu, Adil, Asplund, Anna, Shoaie, Saeed, Kampf, Caroline, Uhlen, Mathias, Nielsen, Jens
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313100/
https://ncbi.nlm.nih.gov/pubmed/25640694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08183
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