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Identifying anti-growth factors for human cancer cell lines through genome-scale metabolic modeling

Human cancer cell lines are used as important model systems to study molecular mechanisms associated with tumor growth, hereunder how genomic and biological heterogeneity found in primary tumors affect cellular phenotypes. We reconstructed Genome scale metabolic models (GEMs) for eleven cell lines b...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Ghaffari, Pouyan, Mardinoglu, Adil, Asplund, Anna, Shoaie, Saeed, Kampf, Caroline, Uhlen, Mathias, Nielsen, Jens
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313100/
https://ncbi.nlm.nih.gov/pubmed/25640694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08183
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