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Identifying anti-growth factors for human cancer cell lines through genome-scale metabolic modeling

Human cancer cell lines are used as important model systems to study molecular mechanisms associated with tumor growth, hereunder how genomic and biological heterogeneity found in primary tumors affect cellular phenotypes. We reconstructed Genome scale metabolic models (GEMs) for eleven cell lines b...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Ghaffari, Pouyan, Mardinoglu, Adil, Asplund, Anna, Shoaie, Saeed, Kampf, Caroline, Uhlen, Mathias, Nielsen, Jens
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313100/
https://ncbi.nlm.nih.gov/pubmed/25640694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08183
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