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Selective degradation of plasmid-derived mRNAs by MCPIP1 RNase

Detection and degradation of foreign nucleic acids is an ancient form of host defense. However, the underlying mechanisms are not completely clear. MCPIP1 is an endoribonuclease and an important regulator in both innate and adaptive immunity by targeting inflammatory mRNA degradation. Here we report...

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Bibliographic Details
Published in:Biochem J
Main Authors: Qian, Yisong, Li, Xiuzhen, Miao, Ruidong, Liu, Shufeng, Xin, Hong-Bo, Huang, Xiaotian, Wang, Tony T., Fu, Mingui
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181959/
https://ncbi.nlm.nih.gov/pubmed/31530713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20190646
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