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DNA:RNA hybrids form at DNA double-strand breaks in transcriptionally active loci
The recent discovery of DNA:RNA hybrids, or R-loops, actively forming at DNA double-strand breaks (DSBs) has unlocked fresh insight into how RNA participates in DNA repair. However, the manner of DSB-induced R-loop formation is vital in determining its mechanism of action and is currently under deba...
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| Udgivet i: | Cell Death Dis |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7181826/ https://ncbi.nlm.nih.gov/pubmed/32332801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2464-6 |
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