Effects of delayed intraventricular TLR7 agonist administration on long-term neurological outcome following asphyxia in the preterm fetal sheep

In the preterm brain, accumulating evidence suggests toll-like receptors (TLRs) are key mediators of the downstream inflammatory pathways triggered by hypoxia-ischemia (HI), which have the potential to exacerbate or ameliorate injury. Recently we demonstrated that central acute administration of the...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Cho, Kenta H. T., Zeng, Nina, Anekal, Praju V., Xu, Bing, Fraser, Mhoyra
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181613/
https://ncbi.nlm.nih.gov/pubmed/32327682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63770-6
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