Induction of Tertiary Phase Epileptiform Discharges after Postasphyxial Infusion of a Toll-Like Receptor 7 Agonist in Preterm Fetal Sheep

Background: Toll-like receptor (TLR) agonists are key immunomodulatory factors that can markedly ameliorate or exacerbate hypoxic–ischemic brain injury. We recently demonstrated that central infusion of the TLR7 agonist Gardiquimod (GDQ) following asphyxia was highly neuroprotective after 3 days but...

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發表在:Int J Mol Sci
Main Authors: Cho, Kenta H.T., Fraser, Mhoyra, Xu, Bing, Dean, Justin M., Gunn, Alistair J., Bennet, Laura
格式: Artigo
語言:Inglês
出版: MDPI 2021
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8234830/
https://ncbi.nlm.nih.gov/pubmed/34205464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126593
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