Stress gates an astrocytic energy reservoir to impair synaptic plasticity

Astrocytes support the energy demands of synaptic transmission and plasticity. Enduring changes in synaptic efficacy are highly sensitive to stress, yet whether changes to astrocyte bioenergetic control of synapses contributes to stress-impaired plasticity is unclear. Here we show in mice that stres...

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Foilsithe in:Nat Commun
Main Authors: Murphy-Royal, Ciaran, Johnston, April D., Boyce, Andrew K. J., Diaz-Castro, Blanca, Institoris, Adam, Peringod, Govind, Zhang, Oliver, Stout, Randy F., Spray, David C., Thompson, Roger J., Khakh, Baljit S., Bains, Jaideep S., Gordon, Grant R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2020
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181611/
https://ncbi.nlm.nih.gov/pubmed/32332733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15778-9
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