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Cholecystokinin Switches the Plasticity of GABA Synapses in the Dorsomedial Hypothalamus via Astrocytic ATP Release

Whether synapses in appetite-regulatory brain regions undergo long-term changes in strength in response to satiety peptides is poorly understood. Here we show that following bursts of afferent activity, the neuromodulator and satiety peptide cholecystokinin (CCK) shifts the plasticity of GABA synaps...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Crosby, Karen M., Murphy-Royal, Ciaran, Wilson, Sarah A., Gordon, Grant R., Bains, Jaideep S., Pittman, Quentin J.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596220/
https://ncbi.nlm.nih.gov/pubmed/30108130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0569-18.2018
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