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Cholecystokinin Switches the Plasticity of GABA Synapses in the Dorsomedial Hypothalamus via Astrocytic ATP Release

Whether synapses in appetite-regulatory brain regions undergo long-term changes in strength in response to satiety peptides is poorly understood. Here we show that following bursts of afferent activity, the neuromodulator and satiety peptide cholecystokinin (CCK) shifts the plasticity of GABA synaps...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Crosby, Karen M., Murphy-Royal, Ciaran, Wilson, Sarah A., Gordon, Grant R., Bains, Jaideep S., Pittman, Quentin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596220/
https://ncbi.nlm.nih.gov/pubmed/30108130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0569-18.2018
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