Stress gates an astrocytic energy reservoir to impair synaptic plasticity

Astrocytes support the energy demands of synaptic transmission and plasticity. Enduring changes in synaptic efficacy are highly sensitive to stress, yet whether changes to astrocyte bioenergetic control of synapses contributes to stress-impaired plasticity is unclear. Here we show in mice that stres...

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Publicado en:Nat Commun
Main Authors: Murphy-Royal, Ciaran, Johnston, April D., Boyce, Andrew K. J., Diaz-Castro, Blanca, Institoris, Adam, Peringod, Govind, Zhang, Oliver, Stout, Randy F., Spray, David C., Thompson, Roger J., Khakh, Baljit S., Bains, Jaideep S., Gordon, Grant R.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181611/
https://ncbi.nlm.nih.gov/pubmed/32332733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15778-9
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