Intracellular Trafficking Mechanisms of Synaptic Dysfunction in Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common neurodegenerative disease characterized by progressive memory loss. Although AD neuropathological hallmarks are extracellular amyloid plaques and intracellular tau tangles, the best correlate of disease progression is synapse loss. What causes synapse loss...

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Udgivet i:Front Cell Neurosci
Main Authors: Perdigão, Catarina, Barata, Mariana A., Araújo, Margarida N., Mirfakhar, Farzaneh S., Castanheira, Jorge, Guimas Almeida, Cláudia
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Cellular Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7180223/
https://ncbi.nlm.nih.gov/pubmed/32362813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00072
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