Diazepam Accelerates GABA(A)R Synaptic Exchange and Alters Intracellular Trafficking

Despite 50+ years of clinical use as anxiolytics, anti-convulsants, and sedative/hypnotic agents, the mechanisms underlying benzodiazepine (BZD) tolerance are poorly understood. BZDs potentiate the actions of gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the adult brain,...

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Xehetasun bibliografikoak
Argitaratua izan da:Front Cell Neurosci
Egile Nagusiak: Lorenz-Guertin, Joshua M., Bambino, Matthew J., Das, Sabyasachi, Weintraub, Susan T., Jacob, Tija C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2019
Gaiak:
Neuroscience
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497791/
https://ncbi.nlm.nih.gov/pubmed/31080408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00163
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