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Diazepam Accelerates GABA(A)R Synaptic Exchange and Alters Intracellular Trafficking
Despite 50+ years of clinical use as anxiolytics, anti-convulsants, and sedative/hypnotic agents, the mechanisms underlying benzodiazepine (BZD) tolerance are poorly understood. BZDs potentiate the actions of gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the adult brain,...
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| Publicado no: | Front Cell Neurosci |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6497791/ https://ncbi.nlm.nih.gov/pubmed/31080408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00163 |
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