TRIM34 restricts HIV-1 and SIV capsids in a TRIM5α-dependent manner

The HIV-1 capsid protein makes up the core of the virion and plays a critical role in early steps of HIV replication. Due to its exposure in the cytoplasm after entry, HIV capsid is a target for host cell factors that act directly to block infection such as TRIM5α and MxB. Several host proteins also...

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Bibliografiska uppgifter
I publikationen:PLoS Pathog
Huvudupphovsmän: Ohainle, Molly, Kim, Kyusik, Komurlu Keceli, Sevnur, Felton, Abby, Campbell, Ed, Luban, Jeremy, Emerman, Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2020
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179944/
https://ncbi.nlm.nih.gov/pubmed/32282853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008507
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