Chargement en cours...

Intestinal restriction of Salmonella Typhimurium requires caspase-1 and caspase-11 epithelial intrinsic inflammasomes

We investigated the role of the inflammasome effector caspases-1 and -11 during Salmonella enterica serovar Typhimurium infection of murine intestinal epithelial cells (IECs). Salmonella burdens were significantly greater in the intestines of caspase-1/11 deficient (Casp1/11(−/−)), Casp1(−/−) and Ca...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Crowley, Shauna M., Han, Xiao, Allaire, Joannie M., Stahl, Martin, Rauch, Isabella, Knodler, Leigh A., Vallance, Bruce A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179941/
https://ncbi.nlm.nih.gov/pubmed/32282854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008498
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!