A46 THE INFLAMMATORY CASPASES COORDINATE MUCOSAL RESTRICTION OF SALMONELLA THROUGH THE EPITHELIAL-INTRINSIC INFLAMMASOME AND IL-22 DRIVEN MUCIN SECRETION

BACKGROUND: Intestinal epithelial cells (IECs) are located at the interface between the gut lumen and the underlying mucosal defense system. Here, they play a central role in the coordination of intestinal homeostasis, tempering pro-inflammatory responses but remaining rapidly responsive to noxious...

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Detalhes bibliográficos
Publicado no:J Can Assoc Gastroenterol
Main Authors: Crowley, S M, Allaire, J M, Han, X, Graef, F A, Stahl, M, Knodler, L, Vallance, B
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Poster of Distinction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043449/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwz047.045
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