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Non-canonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens

Inflammasome-mediated host defenses have been extensively studied in innate immune cells. Whether inflammasomes function for innate defense in intestinal epithelial cells, which represent the first line of defense against enteric pathogens, remains unknown. We observed enhanced Salmonella enterica s...

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Detalhes bibliográficos
Main Authors: Knodler, Leigh A., Crowley, Shauna M., Sham, Ho Pan, Yang, Hyungjun, Wrande, Marie, Ma, Caixia, Ernst, Robert K., Steele-Mortimer, Olivia, Celli, Jean, Vallance, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157630/
https://ncbi.nlm.nih.gov/pubmed/25121752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.07.002
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