A carregar...
FMRP Control of Ribosome Translocation Promotes Chromatin Modifications and Alternative Splicing of Neuronal Genes Linked to Autism
Silencing of FMR1 and loss of its gene product, FMRP, results in fragile X syndrome (FXS). FMRP binds brain mRNAs and inhibits polypeptide elongation. Using ribosome profiling of the hippocampus, we find that ribosome footprint levels in Fmr1-deficient tissue mostly reflect changes in RNA abundance....
Na minha lista:
| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7179797/ https://ncbi.nlm.nih.gov/pubmed/32234480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.02.076 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|