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Accumulation of Major Linezolid Metabolites in Patients with Renal Impairment
In patients with renal impairment (n = 22 of 39), the median serum concentrations of linezolid, PNU-142300, and PNU-142586 were 1.6-, 3.3-, 2.8-fold higher, respectively, than in patients without renal impairment. Metabolite concentrations in paired samples were poorly correlated with linezolid conc...
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| Veröffentlicht in: | Antimicrob Agents Chemother |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7179609/ https://ncbi.nlm.nih.gov/pubmed/32152085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00027-20 |
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