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Reappraisal of Linezolid Dosing in Renal Impairment To Improve Safety

Linezolid is administered as a fixed dose to all patients despite evidence of increased exposure and myelosuppression in renal impairment. The objectives of these studies were to assess the risk of thrombocytopenia with standard-dose linezolid in renal impairment and to identify an alternate dosing...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Crass, Ryan L., Cojutti, Pier Giorgio, Pai, Manjunath P., Pea, Federico
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658752/
https://ncbi.nlm.nih.gov/pubmed/31109977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00605-19
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