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Sustained Co-Evolution in a Stochastic Model of Cancer-Immune Interaction

The dynamic interactions between an evolving malignancy and the adaptive immune system generate diverse evolutionary trajectories which ultimately result in tumor clearance or immune escape. Here, we create a simple mathematical model coupling T-cell recognition with an evolving cancer population wh...

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Publicat a:Cancer Res
Autors principals: George, Jason T., Levine, Herbert
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179478/
https://ncbi.nlm.nih.gov/pubmed/31862779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-2732
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