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Recent Small-Molecule Inhibitors of the p53–MDM2 Protein–Protein Interaction
This review presents the last decade of studies on the synthesis of various types of small-molecule inhibitors of the p53– Mouse double minute 2 homolog (MDM2) protein–protein interaction. The main focus is placed on synthetic approaches to such molecules, their cytotoxicity, and MDM2 binding charac...
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| Publicado en: | Molecules |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7179467/ https://ncbi.nlm.nih.gov/pubmed/32156064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25051211 |
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