載入...

Safety, Tolerability, Pharmacokinetics, and Antimalarial Activity of the Novel Plasmodium Phosphatidylinositol 4-Kinase Inhibitor MMV390048 in Healthy Volunteers

MMV390048 is a novel antimalarial compound that inhibits Plasmodium phosphatidylinositol-4-kinase. The safety, tolerability, pharmacokinetic profile, and antimalarial activity of MMV390048 were determined in healthy volunteers in three separate studies. A first-in-human, double-blind, randomized, pl...

全面介紹

Na minha lista:
書目詳細資料
發表在:Antimicrob Agents Chemother
Main Authors: Sinxadi, Phumla, Donini, Cristina, Johnstone, Hilary, Langdon, Grant, Wiesner, Lubbe, Allen, Elizabeth, Duparc, Stephan, Chalon, Stephan, McCarthy, James S., Lorch, Ulrike, Chibale, Kelly, Möhrle, Jörg, Barnes, Karen I.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2020
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179259/
https://ncbi.nlm.nih.gov/pubmed/31932368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01896-19
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!