MAPK signaling determines lysophosphatidic acid (LPA)-induced inflammation in microglia

BACKGROUND: In the extracellular environment, lysophosphatidic acid (LPA) species are generated via autotaxin (ATX)-mediated hydrolysis of lysophospholipid precursors. Members of the LPA family are potent lipid mediators transmitting signals via six different G protein-coupled LPA receptors (LPAR1-6...

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Publicat a:J Neuroinflammation
Autors principals: Plastira, Ioanna, Bernhart, Eva, Joshi, Lisha, Koyani, Chintan N., Strohmaier, Heimo, Reicher, Helga, Malle, Ernst, Sattler, Wolfgang
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7178949/
https://ncbi.nlm.nih.gov/pubmed/32326963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01809-1
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