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Comparative Pharmacokinetic Profiles of Puerarin in Rat Plasma by UHPLC-MS/MS after Oral Administration of Pueraria lobata Extract and Pure Puerarin

Puerarin is the main biologically active isoflavone in Pueraria lobata and has a wide range of biological activities. However, due to its poor water solubility and low oral bioavailability, its clinical applications are restricted. Compared with puerarin, the Pueraria lobata extract (PLE) has better...

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Detalhes bibliográficos
Publicado no:J Anal Methods Chem
Main Authors: Zhang, Guozhe, Ji, Jianwei, Sun, Mingzhong, Ji, Yuqiao, Ji, Hongjian
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7178524/
https://ncbi.nlm.nih.gov/pubmed/32351754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4258156
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