UHPLC-MS/MS Determination, Pharmacokinetic, and Bioavailability Study of Taxifolin in Rat Plasma after Oral Administration of its Nanodispersion

A rapid and sensitive LC-MS/MS method based on the Triple Quad system has been developed and validated for the determination and pharmacokinetics of taxifolin and its nanodispersion in rat plasma. Taxifolin plasma samples along with butylparaben (internal standard) were pre-treated by liquid-liquid...

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Publicado no:Molecules
Main Authors: Yang, Chun-Juan, Wang, Zhi-Bin, Mi, Ying-Ying, Gao, Ming-Jie, Lv, Jin-Nan, Meng, Yong-Hai, Yang, Bing-You, Kuang, Hai-Xue
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273324/
https://ncbi.nlm.nih.gov/pubmed/27089318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21040494
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