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Determination and Pharmacokinetic Study of Three Diterpenes in Rat Plasma by UHPLC-ESI-MS/MS after Oral Administration of Rosmarinus officinalis L. Extract

Rosmarinus officinalis L. is commonly used as a spice and flavoring agent. Diterpenes are the main active compounds of R. officinalis. An Ultra High Performance Liquid Chromatography-Tandem Mass Spectrometry (UHPLC-ESI-MS/MS) method was developed for the determination of carnosol, rosmanol, and carn...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Wang, Liqian, Gan, Chunli, Wang, Zhibin, Liu, Lu, Gao, Mingjie, Li, Qian, Yang, Chunjuan
Format: Artigo
Langue:Inglês
Publié: MDPI 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152655/
https://ncbi.nlm.nih.gov/pubmed/28587218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22060934
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