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Mechanism of Secondary Ganglioside and Lipid Accumulation in Lysosomal Disease
Gangliosidoses are caused by monogenic defects of a specific hydrolase or an ancillary sphingolipid activator protein essential for a specific step in the catabolism of gangliosides. Such defects in lysosomal function cause a primary accumulation of multiple undegradable gangliosides and glycosphing...
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| 出版年: | Int J Mol Sci |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7178057/ https://ncbi.nlm.nih.gov/pubmed/32272755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21072566 |
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