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Membrane lipids and their degradation compounds control GM2 catabolism at intralysosomal luminal vesicles
The catabolism of ganglioside GM2 is dependent on three gene products. Mutations in any of these genes result in a different type of GM2 gangliosidosis (Tay-Sachs disease, Sandhoff disease, and the B1 and AB variants of GM2 gangliosidosis), with GM2 as the major lysosomal storage compound. GM2 is al...
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| Udgivet i: | J Lipid Res |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Biochemistry and Molecular Biology
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6547633/ https://ncbi.nlm.nih.gov/pubmed/30988135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M092551 |
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