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The Number and Position of Orai3 Units within Heteromeric Store-Operated Ca(2+) Channels Alter the Pharmacology of I(CRAC)

Store-operated heteromeric Orai1/Orai3 channels have been discussed in the context of aging, cancer, and immune cell differentiation. In contrast to homomeric Orai1 channels, they exhibit a different pharmacology upon application of reactive oxygen species (ROS) or 2-aminoethoxydiphenyl borate (2-AP...

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發表在:Int J Mol Sci
Main Authors: Kappel, Sven, Kilch, Tatiana, Baur, Roland, Lochner, Martin, Peinelt, Christine
格式: Artigo
語言:Inglês
出版: MDPI 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7178029/
https://ncbi.nlm.nih.gov/pubmed/32252254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21072458
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