Abnormal Upregulation of GPR17 Receptor Contributes to Oligodendrocyte Dysfunction in SOD1 G93A Mice

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive loss of motor neurons (MN). Importantly, MN degeneration is intimately linked to oligodendrocyte dysfunction and impaired capacity of oligodendrocyte precursor cells (OPCs) to regenerate the myelin sheath...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Bonfanti, Elisabetta, Bonifacino, Tiziana, Raffaele, Stefano, Milanese, Marco, Morgante, Erica, Bonanno, Giambattista, Abbracchio, Maria P., Fumagalli, Marta
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7177925/
https://ncbi.nlm.nih.gov/pubmed/32244295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21072395
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