Abnormal Upregulation of GPR17 Receptor Contributes to Oligodendrocyte Dysfunction in SOD1 G93A Mice

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive loss of motor neurons (MN). Importantly, MN degeneration is intimately linked to oligodendrocyte dysfunction and impaired capacity of oligodendrocyte precursor cells (OPCs) to regenerate the myelin sheath...

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Publicado en:Int J Mol Sci
Autores principales: Bonfanti, Elisabetta, Bonifacino, Tiziana, Raffaele, Stefano, Milanese, Marco, Morgante, Erica, Bonanno, Giambattista, Abbracchio, Maria P., Fumagalli, Marta
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7177925/
https://ncbi.nlm.nih.gov/pubmed/32244295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21072395
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