Unexpected loss of sensitivity to the nicotinic acetylcholine receptor antagonist activity of mecamylamine and dihydro‐β‐erythroidine in nicotine‐tolerant mice

OBJECTIVES: There is a long‐standing interest in developing nicotinic acetylcholine receptor (nAChR) antagonists for concomitant use with nAChR agonists (e.g., nicotine replacement) as complementary smoking cessation aids. Previous studies demonstrate that daily nicotine treatment confers tolerance...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Brain Behav
Egile Nagusiak: de Moura, Fernando B., Wilkerson, Jenny L., McMahon, Lance R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2020
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7177571/
https://ncbi.nlm.nih.gov/pubmed/32092237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.1581
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