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The discriminative stimulus effects of i.v. nicotine in rhesus monkeys: pharmacokinetics and apparent pA(2) analysis with dihydro-β-erythroidine
Quantitative analysis of antagonism is infrequently used to identify nAChRs mediating behavioral effects. Here, nicotine (0.032 mg/kg i.v.) was established as a discriminative stimulus in rhesus monkeys responding under a fixed ratio 5 schedule; pharmacokinetics and underlying nAChR mechanism(s) wer...
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| Publicado no: | Neuropharmacology |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5385163/ https://ncbi.nlm.nih.gov/pubmed/27940077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.12.003 |
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