Discriminative stimulus effects of mecamylamine and nicotine in rhesus monkeys: central and peripheral mechanisms

Mecamylamine is a non-competitive nicotinic acetylcholine receptor (nAChR) antagonist that has been prescribed for hypertension and as an off-label smoking cessation aid. Here, we examined pharmacological mechanisms underlying the interoceptive effects (i.e., discriminative stimulus effects) of meca...

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Bibliographic Details
Published in:Pharmacol Biochem Behav
Main Authors: Cunningham, Colin S., Moerke, Megan J., McMahon, Lance R.
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6788799/
https://ncbi.nlm.nih.gov/pubmed/30738085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2019.02.002
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