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A Peptidomimetic Fluorescent Probe to Detect the Trypsin β2 Subunit of the Human 20S Proteasome

This work describes the chemical synthesis, combinatorial selection, and enzymatic evaluation of peptidomimetic fluorescent substrates specific for the trypsin-like (β2) subunit of the 20S human proteasome. After deconvolution of a library comprising nearly 6000 compounds composed of peg substituted...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Wysocka, Magdalena, Romanowska, Anita, Gruba, Natalia, Michalska, Michalina, Giełdoń, Artur, Lesner, Adam
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7177456/
https://ncbi.nlm.nih.gov/pubmed/32244300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21072396
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