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A Peptidomimetic Fluorescent Probe to Detect the Trypsin β2 Subunit of the Human 20S Proteasome

This work describes the chemical synthesis, combinatorial selection, and enzymatic evaluation of peptidomimetic fluorescent substrates specific for the trypsin-like (β2) subunit of the 20S human proteasome. After deconvolution of a library comprising nearly 6000 compounds composed of peg substituted...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Wysocka, Magdalena, Romanowska, Anita, Gruba, Natalia, Michalska, Michalina, Giełdoń, Artur, Lesner, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7177456/
https://ncbi.nlm.nih.gov/pubmed/32244300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21072396
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