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Development of Large-Scale Downstream Processing for Lentiviral Vectors
The interest in lentiviral vectors (LVs) has increased prominently for gene therapy applications, but few have reached the later stages of clinical trials. The main challenge has remained in scaling up the manufacturing process for the fragile vector to obtain high titers for in vivo usage. We have...
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| 出版年: | Mol Ther Methods Clin Dev |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Gene & Cell Therapy
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7177191/ https://ncbi.nlm.nih.gov/pubmed/32346549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.03.025 |
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