Targeted Gene Expression Profile Reveals CDK4 as Therapeutic Target for Selected Patients With Adrenocortical Carcinoma

Adrenocortical carcinomas (ACC) are aggressive tumors with a heterogeneous prognosis and limited therapeutic options for advanced stages. This study aims to identify novel drug targets for a personalized treatment in ACC. RNA was isolated from 40 formalin-fixed paraffin-embedded ACC samples. We eval...

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Dettagli Bibliografici
Pubblicato in:Front Endocrinol (Lausanne)
Autori principali: Liang, Raimunde, Weigand, Isabel, Lippert, Juliane, Kircher, Stefan, Altieri, Barbara, Steinhauer, Sonja, Hantel, Constanze, Rost, Simone, Rosenwald, Andreas, Kroiss, Matthias, Fassnacht, Martin, Sbiera, Silviu, Ronchi, Cristina L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Endocrinology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176906/
https://ncbi.nlm.nih.gov/pubmed/32373071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.00219
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