NLRP1-Mediated Antidepressant Effect of Ketamine in Chronic Unpredictable Mild Stress Model in Rats

OBJECTIVE: NOD-like receptor protein 1 (NLRP1) inflammasome complex has been recently associated with chronic unpredictable mild stress (CUMS) model of depression. Our aim was to investigate whether ketamine-induced antidepressant effect is associated with suppression of NLRP1. METHODS: Wistar albin...

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Bibliographische Detailangaben
Veröffentlicht in:Psychiatry Investig
Hauptverfasser: Aricioğlu, Feyza, Yalcinkaya, Canan, Ozkartal, Ceren Sahin, Tuzun, Erdem, Sirvanci, Serap, Kucukali, Cem Ismail, Utkan, Tijen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Neuropsychiatric Association 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176563/
https://ncbi.nlm.nih.gov/pubmed/32200609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.30773/pi.2019.0189
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